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Finally, a post-mortem analysis of human brain samples showed increased hippocampal expression of genes encoding for GLP-1R in individuals with severe alcohol-use disorder compared with controls 71
E.Sobrino-PlataJ.Montero-PalmeroM
By enhancing insulin secretion only when blood sugar is high, GIP provides a safety net that reduces the risk of hypoglycaemia
C.A.o.S
As such, it has been used for the management of diabetes for the last few years under the trade name Victoza
In the STEP 1 trial, about 74% of participants on semaglutide experienced GI side effects (nausea, vomiting, diarrhea, or constipation) (source)
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