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GLP-1 may also affect systemic energy metabolism by stimulating thermogenesis in brown adipose tissue and browning of white adipose tissue [43]

If you experience severe, persistent abdominal pain while taking GLP-1 medications, stop taking the medication and seek urgent medical attention, as this could indicate pancreatitis or gallbladder disease

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In the light of the above-mentioned economic burden of CMS, there remains a need for a new comprehensive model that will foster more effective interventions with sustained health effects at reasonable costs