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When NNMT activity is reduced, less nicotinamide is methylated and wasted, allowing NAD pools to remain higher

For this reason, an overdose is very rare and it's generally considered safe, even at high doses

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It supports red blood cell formation and proper nerve function

Figure 5: Low B12 levels in the blood can affect cell and DNA production, mess with energy and hormone balance, and cause proteins to thicken the blood