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The phase 2 trial published in The New England Journal of Medicine in 2023 enrolled adults with obesity without type 2 diabetes and demonstrated dose-dependent weight loss of up to 24.2% of body weight at the highest dose over 48 weeks results that attracted considerable scientific and media attention
Semaglutide Regarding adverse events, both Tirzepatide and Semaglutide demonstrated comparable safety profiles, with GI events being the most frequently reported
Hypokalemia and thrombocytosis could occur upon conversion of severe megaloblastic anemia to normal erythropoiesis with methylcobalamin therapy
Current guidelines for diagnosing PCOS
