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In the SURPASS-2 trial, which directly compared tirzepatide to semaglutide 1 mg for type 2 diabetes, nausea rates were 17-22% for tirzepatide across all three dose levels (5 mg, 10 mg, and 15 mg) versus 18% for semaglutide 1 mg

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Anything that we can do to move that needle forward for these HFpEF patients is of high importance we need to look at those endpoints in another trial or other studies, Tadwalkar concluded.

While semaglutide (a well-known GLP-1) works this way, other related medications have similar effects

Your GP or diabetes specialist will determine your appropriate dose based on clinical assessment, monitoring, and NICE guidance

El Banna, and M.E