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Another strategy is enhancing autologous chondrocyte implantation (ACI)

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Some investigators have indicated that the intracellular form of the parasite arrests the expression of glucose transporters (Silber et al., 2009), and utilizes fatty acids and amino acids taken from the cell cytosol to satisfy its energy needs (Engel et al., 1987

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Because GCLC floxed X Iba1-Cre mice died early (around 34 months of age) due to developmental defects, we could not assess the effect of microglial GCLC-deficiency on brain atrophy

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