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In CIPN in vivo models induced by cisplatin, postmitotic sensory neurons in the dorsal root ganglion (DRG) are particularly sensitive to cisplatin injury, and axonal damage induced by cisplatin involves multiple events, including ROS generation, suggesting that antioxidants may help reduce the neurotoxicity of cisplatin [124, 125]
doi: 10.3390/nu14224886 264 NowellJBluntEEdisonP
other uses are off-label and provider-directed
Its measuring how well the regimens stimulate weight loss and preserve muscle mass
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