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Although PTX exerts significant cytotoxic effects in the treatment of advanced GC, a considerable proportion of patients develop acquired resistance to PTX during administration, ultimately leading to treatment failure 46,47

Thus, plants show a decrease in NADP-ME enzyme activity under stress with 56.63% decrease which were improvised under Al + MT (18.24%) and Al + Se (26.54%) (Fig

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Notably, neither MAO inhibitors nor dopamine agonists appear to affect the composition and function of gut microbiota (Table 4