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A subsequent larger RCT (n=72) confirmed these findings, showing improvements in gait speed, grip strength, exercise capacity, waist circumference, and systolic blood pressure (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline Solubility: 5 mg/mL (14.91 mM)
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This represents a modulatory rather than direct agonist/antagonist profile that distinguishes it from conventional dopaminergic drugs
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