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No, they complement a healthy lifestyle and work best when combined with a balanced diet and exercise

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Experiments conducted on isolated bovine chondrocytes also revealed an apparent upregulation in the production of proteoglycans and collagen in these laboratory settings, fundamental components of the extracellular matrix considered essential for cartilage integrity

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However, murine studies showed no acute toxicity at doses up to 100 mg/kg over 11 weeks, and limited human pilot data through 2026 reported no serious adverse events

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