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Phase 2 trial data (NEJM 2023) showed approximately 17.5% mean body weight reduction at 24 weeks at the highest dose, but week-4 figures were not reported as a primary endpoint
By stimulating lipolysis, they assist in maximizing the fat burned during a calorie deficit or workout
Some patients choose to transition to a lower "maintenance" dose once they reach their target weight, while others may eventually taper off as their lifestyle changes become permanent
Another key part of the transition is ensuring that patients continue to have their blood glucose monitored closely during the switch
Tirzepatide seems to have a greater impact on the absorption of oral birth control than other GLP-1 medications
Obstructive sleep apnoea in obesity: A review
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