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However, this popularity comes with a hefty price tag

The pattern observed in TRIUMPH-4: 2 mg: ~13% mean weight loss 4 mg: ~17% mean weight loss 8 mg: ~24% mean weight loss 12 mg: ~28.7% mean weight loss This positions retatrutide as the first agent capable of routinely producing weight loss greater than 25% territory previously reached only by bariatric surgery

Your provider can also adjust your dosing or treatment plan based on your progress

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Phase 2 trials used a structured titration protocol, typically starting at 0.5 mg once weekly and escalating to maintenance doses of up to 12 mg once weekly