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The primary endpoint was a composite of death from cardiovascular causes, non-fatal MI or non-fatal stroke, with a significant 20% reduction in the semaglutide group versus placebo
These benefits are likely driven by weight loss and improved metabolic health, but the evidence is still limited
In June, Novo Nordisk ended its collaboration with telehealth provider Hims & Hers, citing concerns about "illegal mass compounding and deceptive marketing" of semaglutide products
Its effects on food intake and weight, however, varied between species, as did the degree to which blood sugar was controlled compared with Exendin-4
Slowing the digestive process extends the feelings of fullness and satiety, and altering the bodys hunger cues reduces food cravings