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Changes range from acute inflammatory cell infiltrate(s) or occasional aggregates of lymphocytes/lymphohistiocytic cells/foci of mononuclear cells without associated alterations of adjacent hepatocytes, to large panlobular patches of distinct hepatocyte necrosis accompanied by polymorphonuclear and mononuclear (lymphocytes, plasma cells, macrophages) cellular infiltrates
No, the results are not permanent
You may also discuss potential risks or side effects
The incretins are part of an endogenous system involved in the physiologic regulation of glucose homeostasis
J Biol Chem 1999
This matters because much of the public buzz around these medicines is about weight loss, while many early launches may be positioned first through the diabetes route
