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The supernatants were carefully poured or pipetted into 10 75 mm glass tubes and dried to residue under a nitrogen stream

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Moreover, phenformin, at non-cytotoxic concentrations, had also an indirect anti-cancer effect through modulation of the chemokine milieu within the thyroid tumor microenvironment (inhibition of CXCL8 secretion) (Rotondi et al., 2018)

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