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One frequent mistake is removing the rubber stopper entirely rather than accessing the medication through it with a sterile needle

This occurs through several mechanisms: delayed gastric emptying means food stays in the stomach longer, creating prolonged fullness

- Experienced HRT Patient Reviewer Aug 23, 2025 5 min read Updated: Oct 5, 2025 I've been on Hormone Replacement since December 2019

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Several Pharmacy Planet reviewers noted this specifically, with one observing that by the time the consultation was complete and medication shipped, over a week had passed from the original order