The AMPD2 gene is located on chromosome 1p13.3 and is composed of 20 exons that generate five alternatively spliced mRNAs that collectively encode four distinct protein isoforms
Even though our data show that both agents separately caused cell damage, ethanol potentiated the mucosal injury caused by TNBS, an event that was accompanied by a significant depletion of mucosal GSH levels, suggesting that GSH limitation contributed to enhanced cell injury (Table 1)
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