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Semaglutide, marketed as Wegovy for weight loss, works by mimicking a natural hormone in the body called GLP-1 (glucagon-like peptide-1)
It involved six aspects, which were the bias generated by the randomization process, the bias generated by the randomization sequence, whether the blind method was implemented between participants and researchers, the bias of result evaluation, the bias caused by incomplete result data, and the bias of selective reporting results
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A 2024 analysis published in the Journal of Telemedicine and e-Health found that patients using compounded semaglutide achieved average weight loss of 12-15% over 12 months, comparable to results from branded medication studies (Johnson et al., 2024)
Preserving and building lean mass requires intentional effort beyond just moving more
Health Qual Life Outcomes (2017) 15(1):123
