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Insulin therapy, delivered via subcutaneous (SC) injections or continuous subcutaneous insulin infusion (CSII) systems, remains indispensable, particularly in individuals with T1DM and those with progressive or inadequately controlled T2DM

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The results of the phase 3 clinical trial of retatrutide are eagerly awaited, as it is expected that over a longer time period its efficacy in weight loss will be even greater

doi: 10.1128/CDLI.7.6.920-924.2000 32 TeskeyG.AbrahemR.CaoR.GyurjianK.IslamogluH.LuceroM.et al

Bloem BR, Okun MS, Klein C

Glucose is actively reabsorbed in the proximal convoluted tubule via the Na + -glucose transporter 2 (SGLT2), which couples the transport of the sugar with that of Na + following its electrochemical gradient created by the Na + /K + ATPase on the basolateral membrane of the tubular cells (see Figure 3B)