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The choice of Lipoid S100 and CS concentrations was based on the results of a previous study of the authors Haidy Abbas and Manal El Sheikh that reported the preparation of luteolin loaded chitosomes and investigating their potential in Alzheimers disease management through the intranasal route [66]
Similar approaches have successfully generated cardiac spheroids using rat neonatal ventricular cardiomyocytes, human dermal fibroblasts, and human coronary microartery ECs in ultra-low attachment plates [253], as well as spheroids composed of human iPSC-derived cardiomyocytes, human cardiac fibroblasts, and HUVECs in an ultra-low attachment hanging drop system [254]
Justin Krajeski wrote an earlier version of this article
10.1152/physrev.00034.2006 76
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