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(5) The exposure of research models to AOD9604 has been suggested to restore -AR mRNA levels to those observed in lean controls

Cellular NAD+ NAD+ Preservation By blocking NNMT, 5-Amino-1MQ preserves the cellular NAD+ pool, an essential cofactor for more than 500 metabolic reactions and for the activation of sirtuins

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The optimal time for AOD-9604 administration is in a completely fasted state, typically first thing in the morning upon waking after an overnight fast of 8-10 hours