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Long game
In the liver, it decreases glucose production, while in the pancreas it promotes insulin release and beta-cell proliferation
Sun, H., Saeedi, P., Karuranga, S., Pinkepank, M., Ogurtsova, K., Duncan, B
Switching makes sense if you've plateaued on semaglutide, you're not hitting your blood sugar or metabolic goals, you want the dual-mechanism approach, or you're tolerating semaglutide poorly
23 As shown in TABLE 2 , recommended nonpharmacologic interventions to reduce GI AEs include dietary modifications such as eating smaller, more frequent meals
Los mecanismos mediante los cuales la GLP-1 reduce el apetito incluyen: Accin central en el sistema nervioso: La GLP-1 atraviesa la barrera hematoenceflica en reas especficas o activa vas neurales aferentes que transmiten seales de saciedad al cerebro
