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Nevertheless, the selective targeting of neutrophils using high-affinity ligands presents a challenge because of their close lineage similarity to other myeloid cells (89)
What Is a Peptide
Disruption of the tight endothelial junction can be achieved via the use of a hyperosmotic agent to produce osmotic disruption or use of a vasoactive compound, bradykinin analogs, or other molecules [3]
Trade-offs include less flexibility in dose adjustment and prolonged exposure if adverse effects develop
Mol Cancer Ther 3 : 709714
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