Safety concerns include potential melanoma risk and cardiovascular effects
In 2024 consensus-based guidance was formulated by representatives from the American Society of Anesthesiologists (ASA), the American Gastrointestinal Association (AGA), the American Society for Metabolic and Bariatric Surgery (ASMBS), the International Society of Perioperative Care of Patients with Obesity (ISPCOP), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) [19], according to which, use of GLP-1RAs and the management in the perioperative period should be based on shared decision-making of the patient, the anaesthetist, the prescribing care team, and the surgeon [19, 20]
Assuming rebates of 50% across all GLP-1 products in 2024 would mean net spending of around $14 billion in 2024
The lack of timing-specific guidance in clinical practice reflects the medication's sustained action and stable plasma concentrations achieved with weekly dosing
5 food logging methods make low-hunger or high-craving days easier to manage
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