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The follow-up pivotal trial (METAOD006 / OPTIONS) enrolled a larger cohort and failed to replicate statistically significant weight loss, which led Metabolic Pharmaceuticals to halt the formal drug development program in 2007

short-term ambient excursions during transit do not measurably affect potency

The pharmaceutical formulation disclosed herein may comprise hydroxypropyl-beta-cyclodextrin having a maximum of about 1.0 hydroxypropyls per glucose unit

Both joints depend on ligamentous support to maintain stability during movement

Its use is limited to research settings due to the lack of FDA approval

Clinical studies tested doses ranging from 250mcg to 1mg daily, with 300mcg showing effective fat reduction at the lowest side effect profile