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In pyroptosis-focused research, a phase I trial investigated an autophagy inhibitor (which indirectly enhances pyroptosis by promoting gasdermin E [GSDME] activation) in combination with nivolumab/ipilimumab in 42 patients with metastatic melanoma (171, 172)
An in vitro model of ECD was described using p-cresol [195]
2002 Apr;118(4):565-72
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