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Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

Our group conceived and first developed static rodent and human BBB models using primary cells 5,6,7,8

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Detoxification: In the liver, glutathione conjugates with toxins, making them more water-soluble and easier to excrete through urine or bile

[PMID: 2773253] PubMed record related to this compound for laboratory literature review

Saxenda is approved for adolescents aged 12 and older with obesity, making it the only GLP-1 option besides semaglutide with formal pediatric data