Because of the way it works, it's only FDA-approved for people with certain genetic conditions, namely: Proopiomelanocortin (POMC) deficiency, Proprotein convertase subtilisin/kexin type 1 (PCSK1) deficiency, Leptin receptor (LEPR) deficiency, and Bardet-Biedl syndrome (BBS)
Nenkov M, Ma Y, Galer N, Chen Y
246-262 Yijia Zhang, Cheng Chen, Liping Lu, Kristen L Knutson, Mercedes R Carnethon, Alyce D Fly, Juhua Luo, David M Haas, James M Shikany, Ka Kahe, Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study, Sleep, Volume 45, Issue 4, April 2022, zsab276,
Cytochrome P450 2E1 and its roles in disease
Frequently Asked Questions How long should I wait before concluding that retatrutide is not working
Interaction with Medications: May interact adversely with other medications, leading to dangerous side effects