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Springer-Verlag GmbH Germany, part of Springer Nature: 251263

The dextran sodium sulfate (DSS)-induced colitis animal model in IBD research has several advantages over other chemically induced experimental models owing to its rapidity, simplicity, and reproducibility 13

This active metabolite of vitamin D facilitates immunoprotective response by binding to VDR and activating non-specific as well as specific immune system necessary to mitigate microbial load within oral microenvironment (183, 184)

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