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Pober J.S
Starting at lower dose ranges and titrating based on tolerability and response represents a conservative approach consistent with general peptide therapy principles
Most of us can prevent vitamin B12 deficiency by consuming enough of it in the foods we eat
Dosing information Usual Adult Dose for Pernicious Anemia: Initial dose: 100 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 days If clinical improvement and reticulocyte response is seen from the above dosing: 100 mcg every other day for 7 doses, then: 100 mcg every 3 to 4 days for 2 to 3 weeks, then: Maintenance dose: 100 to 1000 mcg monthly Duration of therapy: Life Comments: Administer concomitant folic acid if needed
10.1016/S0016-5085(19)37201-4 120
The dose is equivalent to a years worth or more of oral iron
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