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These, for example, include prodrug strategies, as seen in the case of OTC, which was designed to have improved bioavailability and stability (it is thought of being converted to cysteine intracellularly, which is then used for GSH synthesis) or NAC amide that has improved lipophilicity and cell permeability
To go back to the car analogy, when both are supported, the engine runs more smoothly and efficiently for the long haul
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Luzindole (LUZ) is a widely used non-selective antagonist of the melatonin receptors MT1 and MT2, enabling us to test whether the effects of exogenous melatonin were receptor-mediated (18, 31, 38, 39)
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Teratogen Carcinogen Mutagen 2002;22: 227234
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