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Some studies suggest a biphasic pattern, with an early peak followed by a nadir and a second rise in GLP-1 concentrations [23], but other studies in humans tend to describe monophasic secretory responses [12, 24, 25]

Glucose, insulin, GLP-1, FGF-19, and FGF-21 were measured and untargeted metabolomics analysis was performed on blood plasma to analyze which hormonal and metabolic systems were altered between patients with and without PBH