Choosing between a medication that increases heart rate and blood pressure versus one that reduces MACE events by 20 percent is not a close call when cardiovascular health is a concern
It is crucial that prescribing clinicians review: Current thyroid function tests (TSH, free T4, free T3) Cardiovascular status and any history of arrhythmias Renal function, particularly if there are concerns about dehydration Pre-existing diabetic retinopathy, which requires close monitoring Concurrent medications and potential drug interactions Patient's ability to recognise and report symptoms of thyroid dysfunction or medication side effects Important considerations before starting Mounjaro include: Pregnancy planning: Mounjaro is not recommended during pregnancy and should be discontinued at least 1 month before a planned pregnancy Oral contraceptive effectiveness may be reduced
A compounded version can make this possible and accessible
Liraglutide was developed earlier and has a shorter half-life of approximately 13 hours, requiring daily dosing
Phase 2 trial data show dose-dependent increases in resting heart rate, alongside favourable reductions in systolic blood pressure and triglycerides
And then have a trip and just do four episodes one day, four episodes, maybe the next day