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PMID: 30709742 Title: Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity Product/Service Type: Biochemicals Science , 364(6436): pii: eaav0748
Outcome of lifestyle intervention in relation to duration of pre-diabetes: the pathobiology and reversibility of prediabetes in a biracial cohort (PROP-ABC) study
The low-dose combination (50/15 mg qd) provided both efficacy and tolerability benefits over pioglitazone 30 mg qd
They may also benefit from longer cycle durations
There was also a positive result for the rate of nonfatal myocardial infarction events, which was lower for the albiglutide group (RR 0.75
Compared with the DPP-4i group, the GLP-1RA group exhibited modest benefits in terms of the composite cardiovascular outcome including cardiovascular death, MI, and ischemic stroke
