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Metabolic adaptation compounds the problem
10.1111/acer.13199 56 SturisJ.GotfredsenC
This flexibility makes adherence easier
Evidence: In major trials, participants achieved substantial weight loss, with higher doses producing the largest average reductions
These changes are often transient and resolve over time, which is another reason trends matter more than any single reading
Acknowledgements We thank Jean-Philippe Leduc-Gaudet, Claire Bnard, Lise Rivollet, and Malika Nadour for constructive comments on the manuscript
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