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Gastroenterology 86(2):274280 Ritzel R, Orskov C, Holst JJ, Nauck MA (1995) Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers
doi: 10.1016/j.carbpol.2019.115072 90 ZhangZXuSWangYYuYLiFZhuHet al
Injection site discomfort Its common to feel slight pain, warmth, or see redness where the IV drip was inserted
Additionally, because GLP-1 receptor agonists slow gastric emptying, the absorption of some oral medicines particularly those with a narrow therapeutic index (such as certain anticoagulants or antiepileptics) may be affected
Some may feel sore after surgery, but this will subside after a few days
In terms of the mechanism of action, statins can act on the calcium channel subunit Cacna2d3 to reduce calpain 1-mediated myocardial mitochondrial apoptosis, thereby exerting a protective effect against myocardial ischemia-reperfusion injury
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