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That distinction matters

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10.1182/blood-2008-03-040253 11 CarmelR.SarraiM

10.1647/1082-6742-34.4.348 41 IlyasU.KatareD

Comparison with structures of the AMY 1 R bound to non-lipidated peptides (CagriBB and rAmy) revealed that the lipid conjugation does not affect the conformation of the peptide, nor the receptor when Cagri is stably engaged

Cagrilintides biggest numbers are combination (CagriSema) results