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The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain

Glutathione depletion can lead to increased oxidative stress, DNA damage, and impaired detoxification

Kraus D, Yang Q, Kong D, et al

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History Glutathione was first discovered in the late nineteenth century and was later identified as a tripeptide composed of glutamine, cysteine, and glycine

In retinal detachment or vascular occlusion, this multi-factorial approach addresses ischemia, inflammation, cell death, and tissue damage simultaneously