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Combined metabolomics and proteomics analysis of major depression in an animal model: perturbed energy metabolism in the chronic mild stressed rat cerebellum

Mercer JJ, Bercovitch L, Muglia JJ

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Declining estrogen and progesterone, combined with relative androgen dominance, can trigger diffuse thinning across the scalp

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It has been found that the ferroptosis inducer, erastin, irreversibly activates CHOP/PUMA within the p53 signaling pathway, thereby enhancing the sensitivity of tumor cells to apoptosis inducers and facilitating apoptosis (Hong et al., 2017)