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Mechanistically, SLC25A39 deficiency induced mitochondrial dysfunction, characterized by excessive mitochondrial reactive oxygen species (ROS), reduced membrane potential, diminished adenosine triphosphate (ATP) synthesis, aberrant mitochondrial permeability transition pore (mPTP) opening, and cytochrome c release
The fundamental difference is the receptor pathway
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doi: 10.1155/2021/5529741 166 MehdizadehkashiARokhgirehSTahermaneshKEslahiNMinaeianSSamimiM
However, pregnant or nursing women, individuals with a medical condition, or those taking prescription medications should consult a healthcare provider before use
10.1074/jbc.M209372200 136 YangW
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