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The results showed that at one hour post-treatment, the ROSE-010 groups had twice as many pain alleviation responders as the placebo group
That does not mean the medication does everything for you
It acts as a nonselective agonist of one of several MCRs
This is not because it is unsafe to have one more often than this, but that it is more in line with the normal dosing regimens for treating people with deficiencies
That eventually leads to dark spots, uneven skin, or patches of colour
PMID 19178874
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