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The treatment protocols consisted of LC administered at a dose of 2 g/day and LAC at 1 g/day, with intervention durations spanning 12 to 24 weeks across the included trials
Tirzepatide at the doses of 10 and 15 mg was noninferior to insulin degludec (primary endpoint) and all three doses of tirzepatide demonstrated superiority in comparison to insulin degludec regarding the change in HbA1c
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