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doi: 10.1016/j.nlm.2010.02.002 56 BenedictCHallschmidMHatkeASchultesBFehmHLBornJet al
Dihexa's preclinical design emphasized brain penetration, and animal studies showed CNS effects
Exclusion criteria for the participation of patients in the fMRI substudy were any medical condition affecting the brain (e.g., stroke, epilepsy, multiple sclerosis), any ferromagnetic nonremovable device, and claustrophobia
The primary way tirzepatide works is by reducing hunger and making patients feel satisfied with less food
The idea for GLP-1s did, in fact, come from research on Gila monsters
Acylcarnitine is a form that enables fatty acids to enter mitochondria for oxidation, the plasma acylcarnitine levels in human circulating blood significantly decrease after UA supplementation (6, 7), indicating an enhancement in mitochondrial -oxidation capacity
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