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"This doesn't mean, however, that you can toss exercise by the wayside
Overall, these findings show that GLP-1R recycling is influenced by persistence of agonist binding within the endosomal compartment, resulting in enhanced insulin-releasing properties of fast-dissociating agonists which maintain an adequate population of cell surface receptors over prolonged periods
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17 Eligible participants were treated with an optimized stable dopaminergic medication regimen (dopamine agonist, levodopa, or monoamine oxidase B [MAO-B] inhibitor, or a combination of these), as determined by the site investigator, for at least 1 month before the baseline initiation of trial agents, with the expectation that the participants could continue the regimen for at least an additional 6 months
doi: 10.3390/ijms21165911 89 IshiiAFurushoMDupreeJLBansalR
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