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doi:10.3390/diseases12090204 24
In rodent models, intracerebroventricular (icv) administration of streptozotocin (STZ) has been widely used to mimic sporadic AD by inducing brain insulin resistance, oxidative stress, and cognitive decline, without affecting peripheral glycemic control
2020;6:eabc2487
Both medications are taken as once-weekly subcutaneous injections and work best alongside a reduced-calorie diet and regular physical activity
Yuan noted that it is important to remember that this was observational data: it shows an association, not causation
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