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Schell C., Kreiskliniken Reutlingen, Department of Neurology
Examples of the evolution of venom components affecting glucose homeostasis include a Glp-1 like gene exendin-4 expressed in the lizard Heloderma suspectum (Gila monster) venom (now underpinning a type 2 diabetes drug 14,15 ), a fish-like insulin mimetic in cone snail venom 16 and the GLP-1 degrading enzyme DPP-4 in venom of various snake species 17
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Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial
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