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To articulate the challenge with simulating antibodies in atomistic detail, Shahfar and colleagues estimated that simulation of a single antibody with sufficient solvent would require 10 Citation5 solvent atoms alone

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These patients rarely see spontaneous improvement and usually require ongoing laxative therapy or dose adjustment

A frequently repeated "half-life ~12.8 days" figure circulates in vendor copy as a rationale for spaced or cyclical dosing

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Staying hydrated and eating a light meal beforehand often helps reduce these symptoms