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The biological impact of GLP-1RAs on cancer risk operates through multiple mechanistic pathways, including direct effects on tumor cell metabolism and proliferation, modulation of immune responses in the tumor microenvironment, and regulation of inflammatory signaling networks (911)

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Slowing the Rate of Digestion GLP-1 receptor agonists slow gastric emptying and the motility of the small intestine

Ghrelin is a peptide produced predominantly by the enteroendocrine cells in the gastric mucosa

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