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Participants received lifestyle support alongside either semaglutide 7.2mg, semaglutide 2.4mg, or placebo

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Like anything being put into the body, they carry possible side effects that must be discovered beforehand

This reaction effectively diverts nicotinamide away from the NAD+ salvage pathway, reducing the cell's capacity to regenerate NAD+

However, pregnancy and certain health conditions may cause increased excretion of carnitine, which could increase risk of deficiency

Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: the STEP 4 Randomized Clinical Trial