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However, as detailed above, cells that exhibit higher levels of mitochondrial activity are less sensitive to 5FU treatment, and those with compromised mitochondrial function are more sensitive, correlating with intrinsic resistance
It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula
it is usually avoided unless the benefits clearly outweigh the risks
Three different tests: Tendon outgrowth , how many cells grow out from a piece of tendon in the dish Wound healing assay , cells are grown as a monolayer, you make a scratch in it and observe how quickly it closes Cell survival , you add peroxide (oxidative stress, which normally kills cells) and observe how many survive What they found: Tenocytes grew faster and in a dose-dependent curve (the more BPC-157, the more growth) The scratch closed 1.8 faster at 1 g/ml BPC-157 Under oxidative stress, 22 % of cells survived without BPC-157, but 67 % with BPC-157 When they blocked the FAK enzyme, the effect disappeared mechanism confirmed Why it matters: This is not just a systemic effect via blood, BPC-157 directly modifies the biology of an individual cell
Many protocols combine them for synergistic effects
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